Description

5-Chloro-2-(Ethylsulfanyl)-n-[2-(Trifluoromethyl)Phenyl]Pyrimidine-4-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active ingredients. This compound matters for its role as a critical building block in modern medicinal chemistry, enabling the development of targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel drugs, particularly in areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) with potential biological activity.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel crop protection agents and pesticides due to its pyrimidine core.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	5-Chloro-2-(Ethylsulfanyl)-n-[2-(Trifluoromethyl)Phenyl]Pyrimidine-4-Carboxamide
CAS No.	832686-28-9
Molecular Formula	C14H11ClF3N3OS
Molecular Weight	361.77 g/mol
Synonyms	5-Chloro-2-(ethylthio)-N-[2-(trifluoromethyl)phenyl]pyrimidine-4-carboxamide; 2-(Ethylthio)-5-chloro-N-[2-(trifluoromethyl)phenyl]pyrimidine-4-carboxamide; 832686-28-9; 5-Chloro-2-ethylsulfanyl-N-[2-(trifluoromethyl)phenyl]pyrimidine-4-carboxamide; 4-Pyrimidinecarboxamide, 5-chloro-2-(ethylthio)-N-[2-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Ethylsulfanyl)-n-[2-(Trifluoromethyl)Phenyl]Pyrimidine-4-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our clients in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.