Description

7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile is a high-value heterocyclic building block featuring a fused pyrazolopyrimidine core substituted with a trifluoromethyl group and a nitrile functionality. This compound is essential for medicinal chemistry research and development, offering unique electronic and steric properties that can significantly modulate the biological activity and pharmacokinetic profiles of candidate molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel small-molecule therapeutics, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as a building block for creating novel active ingredients with enhanced efficacy and environmental profiles.
• Material Science: Potential precursor for the synthesis of advanced organic electronic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile
CAS No.	832115-44-3
Molecular Formula	C8H3F3N4
Molecular Weight	212.13 g/mol
Synonyms	7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile; 7-Trifluoromethyl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile; 7-(Trifluoromethyl)-1H-pyrazolo[1,5-a]pyrimidine-3-carbonitrile; 832115-44-3; Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 7-(trifluoromethyl)-; 7-Trifluoromethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 7-Trifluoromethyl-Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.