Description

1-(6-Methyl-Thieno[2,3-D]Pyrimidin-4-Yl)-Piperidine-4-Carboxylic Acid is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its value lies in its unique molecular architecture, combining a thienopyrimidine core with a piperidine carboxylic acid moiety, making it a versatile building block for constructing novel active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions, pharmaceutical companies, and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas like kinase inhibition and targeted cancer therapies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly for oncology and anti-inflammatory targets.
• Kinase Inhibitor Research: Used as a core scaffold or precursor in the development of potent and selective kinase inhibitors due to the thienopyrimidine pharmacophore.
• Medicinal Chemistry & SAR Studies: Enables structure-activity relationship (SAR) exploration by allowing modifications at the piperidine carboxylic acid position.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study specific biological pathways and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Item	Details
Product Name	1-(6-Methyl-Thieno[2,3-D]Pyrimidin-4-Yl)-Piperidine-4-Carboxylic Acid
CAS No.	831242-24-1
Molecular Formula	C13H15N3O2S
Molecular Weight	277.34 g/mol
Synonyms	1-(6-Methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid; 4-Piperidinecarboxylic acid, 1-(6-methylthieno[2,3-d]pyrimidin-4-yl)-; 831242-24-1; 1-(6-Methyl-thieno[2,3-d]pyrimidin-4-yl)-piperidine-4-carboxylic acid; 6-Methyl-4-(4-piperidyl)thieno[2,3-d]pyrimidine-4-carboxylic acid; TAK-285 intermediate; ARQ 197 related compound
EINECS	Contact for details

Quality Control

Our 1-(6-Methyl-Thieno[2,3-D]Pyrimidin-4-Yl)-Piperidine-4-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure compliance with research and development standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.