Description

5-Bromo-1-(2-Fluoro-6-Trifluoromethyl-Benzyl)-6-Methyl-1H-Pyrimidine-2,4-Dione is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound matters because its unique structure, featuring bromine, fluorine, and trifluoromethyl groups, offers significant potential for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly in medicinal chemistry for hit-to-lead optimization and scaffold diversification.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance lipophilicity and biological activity.
• Chemical Biology Probe Development: Serves as a versatile scaffold for creating tool compounds to study enzyme function and biological pathways.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials due to its halogenated aromatic system.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated pyrimidine derivatives.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in heterocyclic and organofluorine chemistry.

Basic Information

Item	Detail
Product Name	5-Bromo-1-(2-Fluoro-6-Trifluoromethyl-Benzyl)-6-Methyl-1H-Pyrimidine-2,4-Dione
CAS No.	830346-48-0
Molecular Formula	C13H7BrF4N2O2
Molecular Weight	379.11 g/mol
Synonyms	5-Bromo-1-[(2-fluoro-6-(trifluoromethyl)phenyl)methyl]-6-methylpyrimidine-2,4(1H,3H)-dione; 5-Bromo-1-(2-fluoro-6-trifluoromethylbenzyl)-6-methyluracil; 830346-48-0; 5-Bromo-6-methyl-1-[(2-fluoro-6-(trifluoromethyl)phenyl)methyl]uracil; 1-(2-Fluoro-6-(trifluoromethyl)benzyl)-5-bromo-6-methylpyrimidine-2,4(1H,3H)-dione
EINECS	Contact for details

Quality Control

Our 5-Bromo-1-(2-Fluoro-6-Trifluoromethyl-Benzyl)-6-Methyl-1H-Pyrimidine-2,4-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and regulatory compliance ensures a reliable supply for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali; ensure it is stored separately from such materials. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.