Description

Ethyl {[4-(4-Fluorophenyl)Pyrimidin-2-Yl]Thio}Acetate is a high-value organic intermediate featuring a pyrimidine core substituted with a fluorophenyl group and a thioacetate ester side chain. This compound is critical for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Synthesis: Used in the research and production of next-generation fungicides and herbicides.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Material Science: Potential monomer or additive for creating specialty polymers with specific electronic or biological properties.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Ethyl {[4-(4-Fluorophenyl)Pyrimidin-2-Yl]Thio}Acetate
CAS No.	828276-28-4
Molecular Formula	C14H13FN2O2S
Molecular Weight	292.33 g/mol
Synonyms	Ethyl 2-[[4-(4-fluorophenyl)pyrimidin-2-yl]thio]acetate; 2-[[4-(4-Fluorophenyl)-2-pyrimidinyl]thio]acetic Acid Ethyl Ester; Ethyl (4-(4-Fluorophenyl)pyrimidin-2-ylthio)acetate; Acetic acid, 2-[[4-(4-fluorophenyl)-2-pyrimidinyl]thio]-, ethyl ester; Ethyl 2-((4-(4-fluorophenyl)pyrimidin-2-yl)thio)acetate
EINECS	Contact for details

Quality Control

Our production of Ethyl {[4-(4-Fluorophenyl)Pyrimidin-2-Yl]Thio}Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.