Description

4-Cyclopropyl-5-(Furan-2-Yl)-4H-1,2,4-Triazole-3-Thiol is a high-purity, heterocyclic organic compound featuring a unique triazole-thiol core functionalized with cyclopropyl and furan moieties. This specific molecular architecture makes it a versatile and critical building block in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases, inflammation, or central nervous system disorders.
• Agrochemical Research: Used as a core scaffold for developing new-generation fungicides, herbicides, or insecticides with improved efficacy and environmental profiles.
• Ligand Synthesis in Catalysis: The triazole-thiol group can act as a chelating ligand for metal catalysts used in cross-coupling and other organic transformations.
• Material Science Precursor: Potential building block for creating functional polymers or metal-organic frameworks (MOFs) with specific electronic or adsorption properties.
• Bioconjugation Chemistry: The thiol group allows for selective conjugation to biomolecules like proteins or peptides for diagnostic or therapeutic applications.

Basic Information

Product Name	4-Cyclopropyl-5-(Furan-2-Yl)-4H-1,2,4-Triazole-3-Thiol
CAS No.	828274-32-4
Molecular Formula	C9H9N3OS
Molecular Weight	207.25 g/mol
Synonyms	4-Cyclopropyl-5-(2-furyl)-4H-1,2,4-triazole-3-thiol; 5-(2-Furanyl)-4-(cyclopropyl)-4H-1,2,4-triazole-3-thiol; 4-Cyclopropyl-5-(furan-2-yl)-1,2,4-triazole-3-thiol; 3-Thiol-4-cyclopropyl-5-(2-furyl)-1,2,4-triazole; 828274-32-4; 4H-1,2,4-Triazole-3-thiol, 4-cyclopropyl-5-(2-furanyl)-
EINECS	Contact for details

Quality Control

Our 4-Cyclopropyl-5-(Furan-2-Yl)-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.