Description

Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile, 7-(Difluoromethyl)-4,5,6,7-Tetrahydro-5-Methyl- (9Ci) is a high-value, advanced pharmaceutical intermediate characterized by its pyrazolopyrimidine core and difluoromethyl substituent. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced metabolic stability and bioavailability. It is primarily needed by research and development organizations and contract manufacturing organizations (CMOs) in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and synthesis of novel small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its heterocyclic structure.
• Chemical Biology Probe: Serves as a scaffold for creating tool compounds to study biological processes and protein interactions.
• Medicinal Chemistry Library Synthesis: Employed in the construction of diverse compound libraries for high-throughput screening (HTS) campaigns.
• Process Chemistry Development: Utilized in route scouting and optimization for the scalable production of target molecules.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile, 7-(Difluoromethyl)-4,5,6,7-Tetrahydro-5-Methyl- (9Ci)
CAS No.	828272-55-5
Molecular Formula	C9H10F2N4
Molecular Weight	212.20 g/mol
Synonyms	7-(Difluoromethyl)-5-methyl-4,5,6,7-tetrahydro-3-pyrazolo[1,5-a]pyrimidinecarbonitrile; 7-(Difluoromethyl)-5-methyl-4,5,6,7-tetrahydro-3-cyanopyrazolo[1,5-a]pyrimidine; 4,5,6,7-Tetrahydro-7-(difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-3-carbonitrile; Pyrazolo[1,5-a]pyrimidine-3-carbonitrile, 7-(difluoromethyl)-4,5,6,7-tetrahydro-5-methyl-; CAS 828272-55-5
EINECS	Contact for details

Quality Control

Our production of Pyrazolo[1,5-A]Pyrimidine-3-Carbonitrile, 7-(Difluoromethyl)-4,5,6,7-Tetrahydro-5-Methyl- (9Ci) adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by NMR/IR), and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere such as nitrogen or argon when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.