Description

4-Chloro-7-(4-Methoxy-Phenyl)-Thieno[3,2-D]-Pyrimidine is a high-value heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of novel pharmacologically active molecules, particularly kinase inhibitors. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs targeting various therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in the development of assay probes to study specific enzyme pathways and biological mechanisms.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and custom synthesis providers building complex molecular libraries.
• Academic Research: Utilized in university laboratories for methodological development in heterocyclic chemistry and novel reaction exploration.

Basic Information

Product Name	4-Chloro-7-(4-Methoxy-Phenyl)-Thieno[3,2-D]-Pyrimidine
CAS No.	827614-35-7
Molecular Formula	C₁₃H₉ClN₂OS
Molecular Weight	276.74 g/mol
Synonyms	4-Chloro-7-(4-methoxyphenyl)thieno[3,2-d]pyrimidine; 7-(4-Methoxyphenyl)-4-chlorothieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine, 4-chloro-7-(4-methoxyphenyl)-; 827614-35-7; 4-Chloro-7-(p-methoxyphenyl)thieno[3,2-d]pyrimidine; CAS 827614-35-7
EINECS	Contact for details

Quality Control

Our 4-Chloro-7-(4-Methoxy-Phenyl)-Thieno[3,2-D]-Pyrimidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this moisture-sensitive material from humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.