Description

Ethyl 5-Cyclopropyl-7-(Trifluoromethyl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. Pharmaceutical R&D teams and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates with enhanced efficacy and selectivity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective research.
• Agrochemical Research: Serves as a sophisticated scaffold for developing new active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its privileged pyrazolopyrimidine core.
• Material Science Precursor: Potential building block for creating specialty polymers or organic electronic materials with unique fluorinated properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client-specific projects.

Basic Information

Item	Detail
Product Name	Ethyl 5-Cyclopropyl-7-(Trifluoromethyl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-3-Carboxylate
CAS No.	827591-57-1
Molecular Formula	C₁₃H₁₄F₃N₃O₂
Molecular Weight	301.27 g/mol
Synonyms	Ethyl 5-cyclopropyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylate; 5-Cyclopropyl-7-(trifluoromethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxylic acid ethyl ester; 827591-57-1; Pyrazolo[1,5-a]pyrimidine-3-carboxylic acid, 5-cyclopropyl-4,5,6,7-tetrahydro-7-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyclopropyl-7-(Trifluoromethyl)-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrimidine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete batch data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.