Description

Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-Oh is a synthetic, sequence-specific fluorogenic peptide substrate designed for protease activity assays. This compound is critical for biochemical research and pharmaceutical development, enabling precise measurement of enzymatic kinetics and inhibition. It is primarily needed by researchers and quality control laboratories in the life sciences, biotechnology, and pharmaceutical industries for studying proteolytic enzymes.

Application

• Protease Activity Assays: Used as a selective fluorogenic substrate to measure the activity and kinetics of specific proteolytic enzymes.
• Enzyme Inhibition Studies: Essential for high-throughput screening (HTS) to identify and characterize potential protease inhibitors for drug discovery.
• Biochemical Research: A key tool in academic and industrial research for investigating protease function, specificity, and mechanism of action.
• Diagnostic Kit Development: Serves as a core component in the development of in-vitro diagnostic tests for diseases involving dysregulated protease activity.
• Quality Control in Biologics: Employed in QC labs to monitor and validate the purity and activity of enzyme-based biopharmaceutical products.

Basic Information

Product Name	Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-Oh
CAS No.	827044-38-2
Molecular Formula	C48H71N15O14
Molecular Weight	1050.18 g/mol
Synonyms	Abz-GIVRAK(Dnp)-OH; o-Aminobenzoyl-Gly-Ile-Val-Arg-Ala-Lys(2,4-Dinitrophenyl)-OH; Fluorogenic Peptide Substrate Abz-GIVRAK(Dnp)-OH; Protease Substrate VII (specific to target enzyme class); 2,4-DNP-K-ABZ-GIVRA-OH; ABZ-Gly-Ile-Val-Arg-Ala-Lys(DNP)-OH; H-Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-OH
EINECS	Contact for details

Quality Control

Our Abz-Gly-Ile-Val-Arg-Ala-Lys(Dnp)-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow it to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70%
Solubility	Soluble in DMSO, DMF; partly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.