Description

2-(4-Oxoquinazolin-3(4H)-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide is a sophisticated heterocyclic compound that combines quinazolinone and thiadiazole pharmacophores. This molecular architecture makes it a valuable advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing targeted drugs, particularly in oncology and anti-infective fields.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting specific enzymes or receptors.
• Anticancer Agent Research: Used in medicinal chemistry programs to develop potential kinase inhibitors or other targeted cancer therapies.
• Antimicrobial Development: Explored for creating new compounds with antibacterial or antifungal properties, leveraging the thiadiazole moiety.
• Biochemical Research: Employed as a tool compound in biochemical assays to study protein-ligand interactions and signal transduction pathways.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic projects.

Basic Information

Product Name	2-(4-Oxoquinazolin-3(4H)-yl)-N-[5-(propan-2-yl)-1,3,4-thiadiazol-2-yl]acetamide
CAS No.	826996-91-2
Molecular Formula	C₁₅H₁₅N₅O₂S
Molecular Weight	329.38 g/mol
Synonyms	2-(4-Oxo-3,4-dihydroquinazolin-3-yl)-N-(5-isopropyl-1,3,4-thiadiazol-2-yl)acetamide; 3-[2-[(5-Isopropyl-1,3,4-thiadiazol-2-yl)amino]-2-oxoethyl]quinazolin-4(3H)-one; 826996-91-2; Acetamide, 2-(3,4-dihydro-4-oxo-3-quinazolinyl)-N-[5-(1-methylethyl)-1,3,4-thiadiazol-2-yl]-; N-(5-Isopropyl-1,3,4-thiadiazol-2-yl)-2-(4-oxo-3,4-dihydroquinazolin-3-yl)acetamide
EINECS	Contact for details

Quality Control

Our high-purity pharmaceutical intermediate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets exacting R&D standards. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.