Description

7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine, 7-[3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Propyl]-6-(1-Ethoxyethenyl)-5-(4-Methylphenyl)- is a sophisticated, high-purity organic intermediate featuring a complex pyrrolopyrimidine core structure. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of targeted small molecule therapeutics. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in oncology and antiviral research.
• Kinase Inhibitor Development: Used in the research and production of targeted kinase inhibitors due to its pyrrolopyrimidine scaffold.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale manufacturing of complex APIs.
• Custom Synthesis: A vital starting material for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.
• Biochemical Research: Utilized as a probe or reference standard in biochemical assays to study enzyme function and inhibition.
• Academic Research: Supports medicinal chemistry programs in universities and research institutes exploring new heterocyclic compounds.

Basic Information

Product Name	7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine, 7-[3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Propyl]-6-(1-Ethoxyethenyl)-5-(4-Methylphenyl)-
CAS No.	821794-86-9
Molecular Formula	C26H38N4O2Si
Molecular Weight	466.70 g/mol
Synonyms	4-Amino-7-(3-((tert-butyldimethylsilyl)oxy)propyl)-6-(1-ethoxyvinyl)-5-(p-tolyl)-7H-pyrrolo[2,3-d]pyrimidine; 7-(3-((tert-Butyldimethylsilyl)oxy)propyl)-6-(1-ethoxyethenyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; TBDMS-protected Pyrrolopyrimidine Amine Intermediate; 5-(4-Methylphenyl)-6-(1-ethoxyethenyl)-7-[3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]propyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine
EINECS	Contact for details

Quality Control

Our 7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine intermediate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment to ensure traceability and compliance with your research or cGMP guidelines for early-phase development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere or in a dry environment to prevent decomposition. For long-term storage, consider storing under nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.