Description

2-Chloro-4-(3-Pyridin-4-Yl-Ureido)-Benzenesulfonyl Chloride Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonyl chloride and urea functional groups. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition. It is primarily required by research institutions and pharmaceutical companies engaged in the development of small molecule therapeutics, where precise chemical structure and reliable purity are critical for successful outcomes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of biologically active molecules, especially kinase inhibitors and other enzyme-targeting drugs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Serves as a starting material for creating labeled compounds or probes used to study biological pathways and target engagement.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of client-specific compounds for preclinical and clinical trials.

Basic Information

Product Name	2-Chloro-4-(3-Pyridin-4-Yl-Ureido)-Benzenesulfonyl Chloride Hydrochloride
CAS No.	820245-47-4
Molecular Formula	C12H10Cl2N3O3S
Molecular Weight	347.19 g/mol
Synonyms	2-Chloro-4-[(pyridin-4-ylcarbamoyl)amino]benzenesulfonyl chloride hydrochloride; 4-[[(4-Chloro-3-sulfamoylphenyl)carbamoyl]amino]pyridinium chloride; 820245-47-4; 2-Chloro-4-(3-(pyridin-4-yl)ureido)benzenesulfonyl chloride HCl; N-(4-Chloro-3-(chlorosulfonyl)phenyl)-N'-pyridin-4-ylurea hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(3-Pyridin-4-Yl-Ureido)-Benzenesulfonyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.