Description

4-Ethoxy-3-(3-Pyridin-3-Yl-Ureido)-Benzenesulfonyl Chloride Hydrogen Sulfate is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonyl chloride and hydrogen sulfate functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors and other small-molecule drug candidates.
• Chemical Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Serves as a critical reagent in the scale-up and manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use in the development of enzyme inhibitors and probes for biological pathways.
• Custom Synthesis: Starting material for the preparation of specialized sulfonamide and urea derivatives.

Basic Information

Product Name	4-Ethoxy-3-(3-Pyridin-3-Yl-Ureido)-Benzenesulfonyl Chloride Hydrogen Sulfate
CAS No.	820245-43-0
Molecular Formula	C14H14ClN3O6S2
Molecular Weight	419.86 g/mol
Synonyms	4-Ethoxy-3-(3-pyridin-3-ylureido)benzenesulfonyl chloride hydrogen sulfate; 3-(4-Ethoxy-3-sulfamoylphenyl)-1-(pyridin-3-yl)urea hydrogen sulfate (related form); Benzenesulfonyl chloride, 4-ethoxy-3-[[(3-pyridinylamino)carbonyl]amino]-, hydrogen sulfate; 820245-43-0; 3-Pyridinylurea sulfonyl chloride derivative
EINECS	Contact for details

Quality Control

Our production of 4-Ethoxy-3-(3-Pyridin-3-Yl-Ureido)-Benzenesulfonyl Chloride Hydrogen Sulfate adheres to stringent quality protocols suitable for pharmaceutical R&D applications. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.