Description

Ethyl-(4-Trifluoromethyl-Phenyl)-Amine is a specialized aromatic amine derivative featuring a trifluoromethyl substituent, which imparts unique electronic and steric properties. This compound is a valuable building block in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals where the trifluoromethyl group is a key pharmacophore. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in drug discovery and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A critical substrate for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	Ethyl-(4-Trifluoromethyl-Phenyl)-Amine
CAS No.	820209-45-8
Molecular Formula	C9H10F3N
Molecular Weight	189.18 g/mol
Synonyms	N-Ethyl-4-(trifluoromethyl)aniline; 4-(Trifluoromethyl)-N-ethylaniline; N-Ethyl-α,α,α-trifluoro-p-toluidine; 1-Ethylamino-4-trifluoromethylbenzene; p-(Ethylamino)benzotrifluoride; Ethyl(4-trifluoromethylphenyl)amine; 4-Trifluoromethyl-N-ethylaniline; N-Ethyl-4-trifluoromethylbenzenamine
EINECS	Contact for details

Quality Control

Our Ethyl-(4-Trifluoromethyl-Phenyl)-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.