Description

Benzenepropanal, 3,4-Difluoro-2-Hydroxy--Ba--Oxo- (9Ci) is a specialized fluorinated aromatic building block with a unique molecular scaffold. This compound matters as a high-value intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists working on novel active ingredients, where its difluoro and hydroxy-oxo functional groups offer precise control over molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the fluorine atoms enhance biological activity, stability, and lipophilicity.
• Ligand and Catalyst Development: Serves as a precursor for designing novel chelating ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials due to its aromatic and functionalized structure.
• Chemical Biology Probes: Utilized as a building block for creating fluorescent tags or molecular probes to study biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise fluorinated intermediate.

Basic Information

Product Name	Benzenepropanal, 3,4-Difluoro-2-Hydroxy--Ba--Oxo- (9Ci)
CAS No.	816451-05-5
Molecular Formula	C9H6F2O3
Molecular Weight	200.14 g/mol
Synonyms	3,4-Difluoro-2-hydroxy-β-oxobenzene propanal; 2-Hydroxy-3,4-difluoro-β-oxohydrocinnamaldehyde; (3,4-Difluoro-2-hydroxybenzoyl)acetaldehyde; 816451-05-5; 3,4-Difluoro-2-hydroxy-β-oxo-benzenepropanal; 2-Hydroxy-3,4-difluorobenzoylacetaldehyde; 1-(3,4-Difluoro-2-hydroxyphenyl)-3-oxo-1-propanone (tautomeric form)
EINECS	Contact for details

Quality Control

Our Benzenepropanal, 3,4-Difluoro-2-Hydroxy--Ba--Oxo- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.