Description

Fmoc-Arg(Pbf)-Ome CAS NO 813452-47-0 is a protected amino acid derivative widely used in solid-phase peptide synthesis (SPPS). This compound is essential for the controlled and efficient incorporation of arginine into peptide chains, a critical step in the production of complex bioactive peptides and pharmaceutical intermediates. It is a fundamental building block for research institutions, pharmaceutical developers, and CROs/CMOs engaged in peptide-based drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid building block for the sequential assembly of peptide sequences.
• Pharmaceutical Intermediate: Used in the research and GMP-scale production of therapeutic peptides targeting various diseases.
• Bioconjugation & Labeling: Serves as a precursor for introducing arginine residues into modified peptides for biochemical studies.
• Combinatorial Chemistry Libraries: Employed in the generation of diverse peptide libraries for high-throughput screening.
• Academic & Industrial Research: Fundamental reagent for studying protein-protein interactions, enzyme substrates, and peptide hormones.
• Antibiotic & Antiviral Peptide Development: Critical for synthesizing arginine-rich sequences found in many antimicrobial peptides.

Basic Information

Product Name	Fmoc-Arg(Pbf)-Ome
CAS No.	813452-47-0
Molecular Formula	C33H47N5O7S
Molecular Weight	657.83 g/mol
Synonyms	Fmoc-Arg(Pbf)-OMe; Fmoc-L-arginine(Pbf)-O-methyl ester; N-α-Fmoc-N-ω-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine methyl ester; Methyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-[(2,2,4,6,7-pentamethyldihydrobenzofuran-5-yl)sulfonyl]-L-ornithinate; Fmoc-Arg(Pbf)-OMe CAS 813452-47-0; Fmoc-L-Arg(Pbf)-OCH3; Fmoc-Arg(Pbf)-methyl ester
EINECS	Contact for details

Quality Control

Our Fmoc-Arg(Pbf)-Ome is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices and can provide material suitable for research and development under quality guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.