Description

3'-Trifluoromethyl-Biphenyl-3-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and materials science. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for creating specialized aromatic amines used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An essential substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing fluorinated aromatic compounds with specific electronic and steric properties.
• Material Science: Used in the development of polymers and advanced materials where the biphenyl core and fluorine atoms impart desired thermal and chemical resistance.

Basic Information

Product Name	3'-Trifluoromethyl-Biphenyl-3-Ylamine Hydrochloride
CAS No.	811842-42-9
Molecular Formula	C13H11ClF3N
Molecular Weight	273.68 g/mol
Synonyms	[3-(3-Trifluoromethylphenyl)phenyl]amine hydrochloride; 3'-Trifluoromethyl-[1,1'-biphenyl]-3-amine hydrochloride; 3-Amino-3'-trifluoromethylbiphenyl hydrochloride; 3'-Trifluoromethylbiphenyl-3-amine HCl; 3-(3-Trifluoromethylphenyl)aniline hydrochloride; Biphenyl-3-amine, 3'-trifluoromethyl-, hydrochloride; 3'-Trifluoromethyl-3-biphenylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 3'-Trifluoromethyl-Biphenyl-3-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.