Description

2'-Trifluoromethyl-Biphenyl-3-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its specific aromatic amine structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and fine chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the trifluoromethyl group for enhanced bioactivity and stability.
• Material Science: Serves as a precursor for specialty polymers and liquid crystal materials requiring specific aromatic amine functionalities.
• Organic Synthesis: Employed in cross-coupling reactions and as a reagent for introducing the biphenyl-amine moiety into complex molecular architectures.
• Chemical Reference Standard: Used in analytical laboratories for method development and quality control testing of related substances.

Basic Information

Product Name	2'-Trifluoromethyl-Biphenyl-3-Ylamine Hydrochloride
CAS No.	811842-39-4
Molecular Formula	C13H9F3N·HCl
Molecular Weight	275.67 g/mol
Synonyms	3-Amino-2'-trifluoromethylbiphenyl hydrochloride; [1,1'-Biphenyl]-3-amine, 2'-(trifluoromethyl)-, hydrochloride; 2'-(Trifluoromethyl)[1,1'-biphenyl]-3-amine hydrochloride; 2'-Trifluoromethylbiphenyl-3-ylamine hydrochloride; 3-Amino-2'-trifluoromethyl-1,1'-biphenyl hydrochloride
EINECS	Contact for details

Quality Control

Our 2'-Trifluoromethyl-Biphenyl-3-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.