Description

Boc 4-Acetyl-2-Fluoroaniline is a high-purity, protected aniline derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular architecture, particularly in the development of complex pharmaceutical intermediates and agrochemicals. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atom and acetyl group impart specific biological activity and stability.
• Peptide Chemistry & Bioconjugation: The Boc-protected amine is valuable for introducing fluorinated aromatic systems into peptides or for creating site-specific bioconjugation linkers.
• Material Science Research: Employed in the creation of fluorinated organic semiconductors, liquid crystals, or advanced polymers with tailored electronic properties.
• Chemical Biology Probes: Acts as a scaffold for developing fluorescent tags or photoaffinity labels for studying biological systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring high-fidelity fluorinated building blocks.

Basic Information

Product Name	Boc 4-Acetyl-2-Fluoroaniline
CAS No.	811799-54-9
Molecular Formula	C₁₃H₁₆FNO₃
Molecular Weight	253.27 g/mol
Synonyms	1-(4-((tert-Butoxycarbonyl)amino)-3-fluorophenyl)ethan-1-one; tert-Butyl (4-acetyl-2-fluorophenyl)carbamate; N-Boc-4-acetyl-2-fluoroaniline; 4-Acetyl-2-fluoroaniline Boc-protected; 2-Fluoro-4-acetylphenylcarbamic acid tert-butyl ester; Boc-4-acetyl-2-fluoroaniline; N-(tert-Butoxycarbonyl)-4-acetyl-2-fluoroaniline
EINECS	Contact for details

Quality Control

Our Boc 4-Acetyl-2-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.