Description

2-Chloro-4-(Prop-1-Ynyl)Pyrimidine is a high-value pyrimidine derivative, a crucial building block in modern organic synthesis. Its unique halogenated and alkyne-substituted structure makes it an indispensable intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Development: Used to create advanced fungicides, herbicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for functionalized polymers and liquid crystal materials.
• Cross-Coupling Reactions: The chloro and alkyne groups make it an excellent substrate for Sonogashira, Suzuki, and other palladium-catalyzed couplings.
• Chemical Biology Probes: Utilized in the development of molecular probes and labeled compounds for biochemical studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Chloro-4-(Prop-1-Ynyl)Pyrimidine
CAS No.	811450-47-2
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	4-(Prop-1-yn-1-yl)-2-chloropyrimidine; 2-Chloro-4-prop-1-ynylpyrimidine; 2-Chloro-4-(1-propynyl)pyrimidine; Pyrimidine, 2-chloro-4-(1-propynyl)-; 811450-47-2; 2-Chloro-4-propynylpyrimidine
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fine chemical intermediates. Each batch of 2-Chloro-4-(Prop-1-Ynyl)Pyrimidine is analyzed to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC or GC), and impurity profiles is provided with every shipment to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.