Description

5-Fluoropyrimidin-4-Amine is a high-purity fluorinated pyrimidine derivative, a crucial building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. Pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers need this material for creating next-generation compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs and other potential drug candidates targeting various diseases.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom can enhance biological activity and stability.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme mechanisms and biological pathways.
• Material Science: A building block for specialty polymers and advanced organic electronic materials requiring specific heterocyclic structures.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) focused on heterocyclic chemistry.

Basic Information

Product Name	5-Fluoropyrimidin-4-Amine
CAS No.	811450-26-7
Molecular Formula	C4H4FN3
Molecular Weight	113.09 g/mol
Synonyms	4-Amino-5-fluoropyrimidine; 5-Fluoro-4-pyrimidinamine; 5-Fluoro-pyrimidin-4-ylamine; 4-Pyrimidinamine, 5-fluoro-; 5-Fluoro-4-aminopyrimidine
EINECS	Contact for details

Quality Control

Our 5-Fluoropyrimidin-4-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive R&D and scale-up processes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong alkalis and fluorides. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.