Description

Methyl 4,6-Dichloropyrimidine-2-Carboxylate is a high-purity, versatile pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its reactive dichloro and ester functional groups, which enable efficient derivatization for creating complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine core's bioactivity.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential building block for creating specialty polymers, ligands, or organic electronic materials with specific functionalities.
• Custom Synthesis: Serves as a starting material for contract research and manufacturing organizations (CROs/CMOs) to produce tailored derivatives for client projects.

Basic Information

Product Name	Methyl 4,6-Dichloropyrimidine-2-Carboxylate
CAS No.	811450-22-3
Molecular Formula	C6H4Cl2N2O2
Molecular Weight	207.01 g/mol
Synonyms	Methyl 4,6-dichloro-2-pyrimidinecarboxylate; 2-Pyrimidinecarboxylic acid, 4,6-dichloro-, methyl ester; 4,6-Dichloropyrimidine-2-carboxylic acid methyl ester; Methyl 4,6-dichloropyrimidine-2-carboxylate; 4,6-Dichloro-2-pyrimidinecarboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 4,6-Dichloropyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.