Description

Methyl 4-Chloropyrimidine-2-Carboxylate is a high-purity, versatile pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional reactivity, offering both a halogenated pyrimidine core and an ester group for further functionalization, enabling the construction of complex heterocyclic systems. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, including kinase inhibitors, antiviral agents, and other biologically active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require a functionalized pyrimidine scaffold.
• Material Science Research: Serves as a precursor for creating specialized ligands, organic semiconductors, and other functional materials.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and exploring new chemical spaces in heterocyclic chemistry.
• Custom Synthesis Building Block: Provides a versatile starting point for custom synthesis projects requiring specific, high-value pyrimidine derivatives.

Basic Information

Product Name	Methyl 4-Chloropyrimidine-2-Carboxylate
CAS No.	811450-17-6
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	Methyl 4-chloropyrimidine-2-carboxylate; 4-Chloro-2-pyrimidinecarboxylic acid methyl ester; Methyl 4-chloro-2-pyrimidinecarboxylate; 2-Pyrimidinecarboxylic acid, 4-chloro-, methyl ester; 811450-17-6; Methyl 4-chloropyrimidine-2-carboxylate CAS 811450-17-6
EINECS	Contact for details

Quality Control

Our Methyl 4-Chloropyrimidine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.