Description

5-Methoxy-2-(Trifluoromethyl)-4-Pyrimidinol is a high-value pyrimidine derivative characterized by its methoxy and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, particularly in antiviral and anticancer therapies.
• Agrochemical Synthesis: Serves as a precursor for novel herbicides, fungicides, and insecticides, leveraging the biological activity of the pyrimidine core.
• Chemical Research: A valuable fluorinated building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Potential use in the synthesis of specialty polymers and advanced materials that require fluorinated aromatic components.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5-Methoxy-2-(Trifluoromethyl)-4-Pyrimidinol
CAS No.	808770-42-5
Molecular Formula	C6H5F3N2O2
Molecular Weight	194.11 g/mol
Synonyms	5-Methoxy-2-(trifluoromethyl)pyrimidin-4-ol; 4-Pyrimidinol, 5-methoxy-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-5-methoxypyrimidin-4-ol; 5-Methoxy-2-trifluoromethyl-4-hydroxypyrimidine; 4-Hydroxy-5-methoxy-2-(trifluoromethyl)pyrimidine
EINECS	Contact for details

Quality Control

Our production of 5-Methoxy-2-(Trifluoromethyl)-4-Pyrimidinol adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure high purity and consistent chemical identity. Comprehensive Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.