Description

4-Chloro-5-Methoxy-2-(Trifluoromethyl)Pyrimidine is a high-value, multi-functional pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and chloro-methoxy substitution pattern makes it an indispensable intermediate for creating novel compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel small-molecule drugs, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and lipophilicity.
• Material Science Research: Serves as a precursor for the synthesis of specialty chemicals, liquid crystals, and functional materials requiring specific electronic properties.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes and tool compounds to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	4-Chloro-5-Methoxy-2-(Trifluoromethyl)Pyrimidine
CAS No.	808770-41-4
Molecular Formula	C6H4ClF3N2O
Molecular Weight	212.56 g/mol
Synonyms	2-(Trifluoromethyl)-4-chloro-5-methoxypyrimidine; 4-Chloro-5-methoxy-2-(trifluoromethyl)pyrimidine; 5-Methoxy-4-chloro-2-trifluoromethylpyrimidine; 808770-41-4; Pyrimidine, 4-chloro-5-methoxy-2-(trifluoromethyl)-; 4-Chloro-5-methoxy-2-trifluoromethylpyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Methoxy-2-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and traceability ensures you receive a product that meets your precise research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.