Description

5-Chloro-2-Methoxy-4-Pyrimidinamine is a high-purity pyrimidine derivative, a crucial building block in advanced organic synthesis. Its value lies in its functionalized heterocyclic structure, which serves as a versatile intermediate for creating complex molecules with targeted biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of active pharmaceutical ingredients (APIs), especially for antiviral, anticancer, and kinase inhibitor compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty dyes, pigments, and other performance chemicals requiring specific pyrimidine motifs.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	5-Chloro-2-Methoxy-4-Pyrimidinamine
CAS No.	807329-88-0
Molecular Formula	C5H6ClN3O
Molecular Weight	159.57 g/mol
Synonyms	4-Amino-5-chloro-2-methoxypyrimidine; 5-Chloro-2-methoxy-4-pyrimidinamine; 5-Chloro-2-methoxypyrimidin-4-amine; 4-Pyrimidinamine, 5-chloro-2-methoxy-; 2-Methoxy-5-chloro-4-pyrimidinamine; 5-Chloro-4-amino-2-methoxypyrimidine; 5-Chloro-2-methoxy-4-aminopyrimidine
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methoxy-4-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP and research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.