Description

4-[2-Phenyl-5,7-Bis(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidin-3-Yl]Phenol is a high-value, multi-functional heterocyclic compound featuring a pyrazolopyrimidine core substituted with phenol and trifluoromethyl groups. This unique structure provides exceptional chemical stability and reactivity, making it a critical advanced intermediate for demanding synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients, where its trifluoromethyl groups are prized for enhancing metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor for developing new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Used in the research and development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, fluorinated aromatic structure.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization in medicinal and combinatorial chemistry for library generation.
• Life Science Research: Employed as a biochemical tool or probe in academic and industrial research to study enzyme inhibition and biological pathways.

Basic Information

Item	Details
Product Name	4-[2-Phenyl-5,7-Bis(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidin-3-Yl]Phenol
CAS No.	805239-56-9
Molecular Formula	C21H11F6N3O
Molecular Weight	435.33 g/mol
Synonyms	3-(4-Hydroxyphenyl)-2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; Phenol, 4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-; 805239-56-9; 2-Phenyl-3-(4-hydroxyphenyl)-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine; Pyrazolo[1,5-a]pyrimidine, 4-[2-phenyl-5,7-bis(trifluoromethyl)-3-yl]phenol derivative
EINECS	Contact for details

Quality Control

Every batch of 4-[2-Phenyl-5,7-Bis(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidin-3-Yl]Phenol is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as verified by HPLC, NMR, and MS. Our quality commitment ensures consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.