Description

Uracil, 6-(Aminomethyl)-5-Bromo- (8Ci) is a halogenated and functionalized pyrimidine derivative, a key heterocyclic scaffold in medicinal chemistry and life sciences research. This compound is specifically engineered as a versatile building block for the synthesis of novel nucleoside analogs and pharmaceutical intermediates. It is primarily utilized by researchers and process chemists in the pharmaceutical and biotechnology sectors for drug discovery programs targeting antiviral and anticancer therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Probe Development: Used to create labeled or modified uracil derivatives for studying enzyme mechanisms and nucleic acid interactions.
• Organic Synthesis: Acts as a specialized substrate for cross-coupling reactions and further functionalization due to the reactive bromo and aminomethyl groups.
• Academic & Institutional Research: Employed in universities and research institutes for fundamental studies in chemical biology and organic chemistry.

Basic Information

Product Name	Uracil, 6-(Aminomethyl)-5-Bromo- (8Ci)
CAS No.	802895-55-2
Molecular Formula	C5H6BrN3O2
Molecular Weight	220.03 g/mol
Synonyms	5-Bromo-6-(aminomethyl)uracil; 5-Bromo-6-(aminomethyl)-2,4(1H,3H)-pyrimidinedione; 6-(Aminomethyl)-5-bromouracil; 5-Bromo-6-(aminomethyl)-1H-pyrimidine-2,4-dione; 802895-55-2 (CAS)
EINECS	Contact for details

Quality Control

Our Uracil, 6-(Aminomethyl)-5-Bromo- (8Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key specifications such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.