Description

4H-Pyrimido[2,1-B]Quinazolin-4-One,2,3,6,11-Tetrahydro-11-Methyl-(8Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of new chemical entities (NCEs) for drug discovery programs.
• API Synthesis: Used in the development and scale-up of Active Pharmaceutical Ingredients (APIs) targeting central nervous system (CNS) disorders or other specialized therapeutic areas.
• Medicinal Chemistry Research: Provides a versatile heterocyclic core for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D labs.
• Process Chemistry: Employed in route scouting and process optimization for the efficient and scalable manufacturing of complex drug molecules.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	4H-Pyrimido[2,1-B]Quinazolin-4-One,2,3,6,11-Tetrahydro-11-Methyl-(8Ci)
CAS No.	802322-27-6
Molecular Formula	C12H11N3O
Molecular Weight	213.24 g/mol
Synonyms	2,3,6,11-Tetrahydro-11-methyl-4H-pyrimido[2,1-b]quinazolin-4-one; 11-Methyl-2,3,6,11-tetrahydro-4H-pyrimido[2,1-b]quinazolin-4-one; Pyrimido[2,1-b]quinazolin-4-one, 2,3,6,11-tetrahydro-11-methyl-; SCHEMBL21806227; AKOS040759256; ZINC000003799755; A1-00819
EINECS	Contact for details

Quality Control

Our 4H-Pyrimido[2,1-B]Quinazolin-4-One,2,3,6,11-Tetrahydro-11-Methyl-(8Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.