Description

Pyrimidine, 1,4,5,6-Tetrahydro-2-[2-(3-Methyl-2-Thienyl)Vinyl]-, (E)- (8Ci) is a specialized heterocyclic organic compound featuring a pyrimidine core fused with a thiophene moiety via a vinyl linker. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a potential electron-transport or emissive layer material due to its conjugated system.
• Ligand in Catalysis: Can be functionalized to create novel ligands for transition metal catalysts used in cross-coupling reactions.
• Chemical Biology Probes: Employed in the design of molecular probes to study biological pathways and protein functions.

Basic Information

Product Name	Pyrimidine, 1,4,5,6-Tetrahydro-2-[2-(3-Methyl-2-Thienyl)Vinyl]-, (E)- (8Ci)
CAS No.	802030-14-4
Molecular Formula	C11H14N2S
Molecular Weight	206.31 g/mol
Synonyms	(E)-2-[2-(3-Methylthiophen-2-yl)vinyl]-1,4,5,6-tetrahydropyrimidine; 1,4,5,6-Tetrahydro-2-[(E)-2-(3-methyl-2-thienyl)vinyl]pyrimidine; (E)-1,4,5,6-Tetrahydro-2-(2-(3-methylthiophen-2-yl)vinyl)pyrimidine; 2-[(1E)-2-(3-Methyl-2-thienyl)ethenyl]-1,4,5,6-tetrahydropyrimidine; CAS 802030-14-4
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 1,4,5,6-Tetrahydro-2-[2-(3-Methyl-2-Thienyl)Vinyl]-, (E)- (8Ci) adheres to stringent quality protocols suitable for research and development applications. All batches undergo comprehensive analytical characterization including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical quality attributes. We support cGMP compliance for advanced pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.