Description

4-Pyrimidinethiol,5-(Bromomethyl)-2-Methyl-(8Ci) is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both a bromomethyl group and a thiol moiety, makes it a versatile precursor for constructing complex molecular frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and plant growth regulators requiring specific heterocyclic cores.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Chemical Biology Probes: Useful for synthesizing activity-based probes and bioconjugation reagents due to its reactive thiol and alkyl halide functionalities.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Pyrimidinethiol,5-(Bromomethyl)-2-Methyl-(8Ci)
CAS No.	801989-89-9
Molecular Formula	C6H7BrN2S
Molecular Weight	219.10 g/mol
Synonyms	5-(Bromomethyl)-2-methylpyrimidine-4-thiol; 2-Methyl-5-(bromomethyl)-4-pyrimidinethiol; 4(1H)-Pyrimidinethione, 5-(bromomethyl)-2-methyl-; 5-(Bromomethyl)-2-methyl-4-pyrimidinethiol; 801989-89-9; 4-Pyrimidinethiol, 5-(bromomethyl)-2-methyl- (8CI)
EINECS	Contact for details

Quality Control

Every batch of 4-Pyrimidinethiol,5-(Bromomethyl)-2-Methyl-(8Ci) is manufactured under strict quality management protocols. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods (HPLC, NMR, MS) is supplied with each shipment to guarantee reproducible results and supply chain integrity for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity, keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.