Description

2-(n-Boc)Amino-6-Methoxyfluorobenzene is a high-purity, protected aniline derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a reactive aromatic amine group protected by a tert-butoxycarbonyl (Boc) group, which is stable under a wide range of reaction conditions yet readily cleaved under mild acidic conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex molecules in drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluoromethoxy aniline moiety imparts desired biological activity.
• Peptide Mimetics & Conjugates: Facilitates the incorporation of fluorinated aromatic amino acid analogs into peptide chains for medicinal chemistry studies.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for advanced polymers and functional organic materials.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-(n-Boc)Amino-6-Methoxyfluorobenzene
CAS No.	801281-99-2
Molecular Formula	C₁₂H₁₆FNO₃
Molecular Weight	241.26 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-6-methoxyfluorobenzene; 2-Fluoro-6-methoxy-N-Boc-aniline; 1-(tert-Butoxycarbonylamino)-2-fluoro-3-methoxybenzene; tert-Butyl (2-fluoro-6-methoxyphenyl)carbamate; N-Boc-2-fluoro-6-methoxyaniline; Boc-2-F-6-MeO-Aniline; 2-Fluoro-6-methoxybenzenamine, N-Boc derivative; 801281-99-2
EINECS	Contact for details

Quality Control

Our 2-(n-Boc)Amino-6-Methoxyfluorobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.