Description

(Cys(Acm)20,31)-Egf (20-31) CAS NO 89991-90-2 is a synthetic peptide fragment derived from the Epidermal Growth Factor (EGF) protein, specifically encompassing amino acids 20 to 31 with protected cysteine residues. This modified peptide is a critical research-grade intermediate for studying protein-protein interactions, disulfide bond formation, and the structure-activity relationships of EGF. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research institutions focused on oncology, wound healing, and cell signaling pathways.

Application

• Biochemical Research: Used as a key intermediate in the study of EGF receptor binding and signal transduction mechanisms.
• Peptide Synthesis: Serves as a building block for the solid-phase or solution-phase synthesis of longer, modified EGF analogs and conjugates.
• Structure-Activity Relationship (SAR) Studies: Essential for investigating the role of specific cysteine residues and disulfide bridges in EGF's biological activity and stability.
• Reference Standard: Employed as a high-purity calibrant or control in analytical methods such as HPLC and mass spectrometry for peptide characterization.
• Drug Discovery: A valuable tool in the development of novel therapeutics targeting the EGF pathway in cancers and regenerative medicine.

Basic Information

Product Name	(Cys(Acm)20,31)-Egf (20-31)
CAS No.	89991-90-2
Molecular Formula	C58H89N17O19S2
Molecular Weight	1384.6 g/mol
Synonyms	EGF (20-31), Acm-Cys-EGF(20-31); Epidermal Growth Factor Fragment 20-31, Cys(Acm) protected; H-Cys(Acm)-Asp-Leu-Gly-Tyr-Val-Leu-Asp-Lys-Phe-Cys(Acm)-OH; Acm-Protected EGF Peptide; [Acm-Cys20, Acm-Cys31]-EGF(20-31); EGF (20-31) Disulfide Bridge Precursor
EINECS	Contact for details

Quality Control

Our (Cys(Acm)20,31)-Egf (20-31) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for peptide synthesis, ensuring reliable performance in your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ±10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.