Description

Ethyl 5-Chloro-6-Hydroxy-2-Methylpyrimidine-4-Carboxylate is a high-purity pyrimidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile scaffold for medicinal chemistry and material science research programs.
• Fine Chemical Production: Intermediate for manufacturing complex, high-value specialty chemicals and dyes.
• Academic & Contract Research: Essential reagent for university laboratories and CROs (Contract Research Organizations) exploring heterocyclic chemistry.

Basic Information

Product Name	Ethyl 5-Chloro-6-Hydroxy-2-Methylpyrimidine-4-Carboxylate
CAS No.	89981-35-1
Molecular Formula	C9H9ClN2O3
Molecular Weight	228.63 g/mol
Synonyms	5-Chloro-6-hydroxy-2-methylpyrimidine-4-carboxylic acid ethyl ester; Ethyl 5-chloro-6-hydroxy-2-methyl-4-pyrimidinecarboxylate; 4-Pyrimidinecarboxylic acid, 5-chloro-6-hydroxy-2-methyl-, ethyl ester; 89981-35-1; 5-Chloro-6-hydroxy-2-methyl-4-pyrimidinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-Chloro-6-Hydroxy-2-Methylpyrimidine-4-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.