Description

3-(5-Amino-6-Chloro-Pyrimidin-4-Ylamino)-Propan-1-Ol is a high-purity pyrimidine derivative building block of significant importance in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly in antiviral and anticancer research. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for constructing complex molecular architectures where precise functional group placement is critical.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel nucleoside analogs and other heterocyclic APIs.
• Antiviral Drug Research: Used in the development of compounds targeting viral replication mechanisms.
• Oncology Research: Serves as a precursor in the creation of potential kinase inhibitors and other targeted cancer therapies.
• Agrochemical Synthesis: Employed in the research and development of new generation herbicides and fungicides.
• Biochemical Probe Development: Utilized to create labeled compounds and probes for studying enzymatic processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	3-(5-Amino-6-Chloro-Pyrimidin-4-Ylamino)-Propan-1-Ol
CAS No.	89893-31-2
Molecular Formula	C7H11ClN4O
Molecular Weight	202.64 g/mol
Synonyms	3-[(5-Amino-6-chloro-4-pyrimidinyl)amino]-1-propanol; 1-Propanol, 3-[(5-amino-6-chloro-4-pyrimidinyl)amino]-; 5-Amino-6-chloro-N-(3-hydroxypropyl)pyrimidin-4-amine; 89893-31-2; 3-(5-Amino-6-chloro-pyrimidin-4-ylamino)-propan-1-ol; 4-Amino-5-chloro-6-[(3-hydroxypropyl)amino]pyrimidine
EINECS	Contact for details

Quality Control

Our 3-(5-Amino-6-Chloro-Pyrimidin-4-Ylamino)-Propan-1-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by HPLC, NMR, and MS. Our quality commitment aligns with ICH guidelines, and we can support development projects requiring regulatory starting material documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.