Description

Cytosine, n-Acetyl-5-Fluoro- (7Ci) is a fluorinated and acetylated derivative of the nucleobase cytosine, serving as a key synthetic intermediate in advanced organic chemistry. This compound is valued for its role in modifying nucleoside structures, enabling the development of novel compounds with targeted biological activity. It is primarily required by researchers and manufacturers in the pharmaceutical and agrochemical sectors for applications in drug discovery, nucleotide synthesis, and the creation of specialized biochemical probes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of fluorinated nucleoside analogs and potential antiviral or anticancer prodrugs.
• Biochemical Research: Used in studies investigating DNA/RNA metabolism, enzyme inhibition, and the structure-activity relationships of modified nucleosides.
• Agrochemical Development: Serves as a precursor in creating novel compounds with potential herbicidal or pesticidal activity.
• Diagnostic Reagent Synthesis: Employed in the production of labeled nucleotides and probes for molecular diagnostics and imaging.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploratory synthetic chemistry projects.

Basic Information

Product Name	Cytosine, n-Acetyl-5-Fluoro- (7Ci)
CAS No.	89829-72-1
Molecular Formula	C6H6FN3O2
Molecular Weight	171.13 g/mol
Synonyms	5-Fluoro-N-acetylcytosine; 1-(5-Fluoro-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)ethan-1-one; N-Acetyl-5-fluorocytosine; 5-Fluoro-1H-pyrimidine-2,4-dione, 1-acetyl-; 1-Acetyl-5-fluorouracil (related structure); 5-Fluorocytosine N-acetate; 5-Fluoro-1-acetylcytosine; 5-FC Acetamide
EINECS	Contact for details

Quality Control

Our Cytosine, n-Acetyl-5-Fluoro- (7Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.