Description

2,2-Difluoro-Benzo[1,3]Dioxole-4-Sulfonyl Chloride is a high-value, multi-functional chemical intermediate characterized by its reactive sulfonyl chloride group and difluorinated benzodioxole core. This compound is essential for introducing the 2,2-difluorobenzodioxole sulfonyl moiety into target molecules, enabling the synthesis of advanced materials and active ingredients. It is primarily sought by research and development teams and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing sulfonamide-based drugs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the difluorobenzodioxole group confers stability and bioactivity.
• Material Science Research: Serves as a precursor for functional polymers, dyes, and liquid crystals, leveraging its unique electronic properties.
• Chemical Biology Probes: Employed in developing molecular probes and labeling reagents due to the reactivity of the sulfonyl chloride group.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,2-Difluoro-Benzo[1,3]Dioxole-4-Sulfonyl Chloride
CAS No.	89819-42-1
Molecular Formula	C7H3ClF2O4S
Molecular Weight	256.61 g/mol
Synonyms	4-(Chlorosulfonyl)-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-1,3-benzodioxole-4-sulfonyl chloride; 2,2-Difluorobenzo[d][1,3]dioxole-4-sulfonyl chloride; 1,3-Benzodioxole, 2,2-difluoro-4-(chlorosulfonyl)-; 89819-42-1; 2,2-Difluoro-4-sulfonylchloride-1,3-benzodioxole
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-Benzo[1,3]Dioxole-4-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.