Description

Rolafagrel is a synthetic organic compound with significant pharmacological research interest. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and development processes. Rolafagrel CAS NO 89781-55-5 represents a high-purity chemical building block essential for advancing medicinal chemistry projects.

Application

• Pharmaceutical Research & Development: Serves as a critical intermediate in the synthesis of investigational new drugs targeting specific biological pathways.
• Medicinal Chemistry Studies: Used as a reference standard or building block for structure-activity relationship (SAR) optimization in drug discovery programs.
• Biochemical Research: Employed in in vitro assays to study enzyme inhibition or receptor binding mechanisms.
• API Manufacturing: Acts as a precursor in the multi-step synthesis of complex active pharmaceutical ingredients under current Good Manufacturing Practice (cGMP) conditions.
• Contract Research Organizations (CROs): Supplied to CROs for client-sponsored preclinical research and development.

Basic Information

Product Name	Rolafagrel
CAS No.	89781-55-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Rolafagrel; 89781-55-5; 4-(4-Methoxyphenyl)-1,2,3,6-tetrahydro-1-(3-pyridinylmethyl)pyridine; 1-(3-Pyridinylmethyl)-4-(4-methoxyphenyl)-1,2,3,6-tetrahydropyridine; 4-(4-Methoxyphenyl)-1-(pyridin-3-ylmethyl)-1,2,3,6-tetrahydropyridine
EINECS	Contact for details

Quality Control

Our Rolafagrel is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via advanced techniques like HPLC and GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom synthesis and purification to meet specific pharmacopeial or internal standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.