Description

Proline, 3-Hydroxy-5-Oxo-, Ethyl Ester (7Ci) is a specialized proline derivative that serves as a valuable chiral building block and intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity, structurally defined molecules for pharmaceutical and agrochemical development. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for applications in drug discovery, peptide mimetics, and the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other enzyme-targeted therapies.
• Peptidomimetics Research: Used in medicinal chemistry to design and synthesize peptide analogs with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for developing advanced, chiral pesticides and herbicides with specific modes of action.
• Bioconjugation & Probe Development: Employed in the creation of biochemical probes and labeled compounds for diagnostic and research applications.
• Asymmetric Catalysis: Can be utilized as a precursor for chiral ligands or catalysts in enantioselective synthesis.
• Academic & R&D: A valuable reagent for university and corporate research laboratories exploring new synthetic methodologies and bioactive compound libraries.

Basic Information

Product Name	Proline, 3-Hydroxy-5-Oxo-, Ethyl Ester (7Ci)
CAS No.	89775-97-3
Molecular Formula	C8H11NO4
Molecular Weight	185.18 g/mol
Synonyms	Ethyl 3-Hydroxy-5-oxoproline; Ethyl 3-Hydroxy-5-oxo-L-prolinate; 3-Hydroxy-5-oxoproline Ethyl Ester; 5-Oxo-3-hydroxyproline Ethyl Ester; L-Proline, 3-hydroxy-5-oxo-, ethyl ester; (2S,3S)-3-Hydroxy-5-oxopyrrolidine-2-carboxylic acid ethyl ester; 7CI Name: Proline, 3-hydroxy-5-oxo-, ethyl ester
EINECS	Contact for details

Quality Control

We supply Proline, 3-Hydroxy-5-Oxo-, Ethyl Ester (7Ci) to high-purity standards suitable for research and commercial synthesis. Our rigorous quality testing includes identity confirmation, purity assay, and impurity profiling to ensure batch-to-batch consistency and reliability. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.