Description

6-(Chloromethyl)-2-(Methylthio)Pyrimidin-4(3H)-One is a versatile heterocyclic building block, primarily valued for its reactive chloromethyl and methylthio functional groups. This compound is essential for the synthesis of more complex pyrimidine derivatives, which are core structures in numerous active pharmaceutical ingredients (APIs) and agrochemicals. It is a critical intermediate for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of antiviral, anticancer, and other therapeutic pyrimidine-based APIs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the pyrimidine core provides essential biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for creating compound libraries and exploring structure-activity relationships (SAR).
• Specialty Chemical Production: Intermediate in the manufacture of dyes, photoinitiators, and other functional materials.
• Nucleoside Analogue Synthesis: Potential precursor in the development of modified nucleosides for biochemical applications.

Basic Information

Product Name	6-(Chloromethyl)-2-(Methylthio)Pyrimidin-4(3H)-One
CAS No.	89639-37-2
Molecular Formula	C6H7ClN2OS
Molecular Weight	190.65 g/mol
Synonyms	4(3H)-Pyrimidinone, 6-(chloromethyl)-2-(methylthio)-; 2-(Methylthio)-6-(chloromethyl)pyrimidin-4(3H)-one; 6-Chloromethyl-2-methylmercapto-4-pyrimidinol; 2-Methylthio-6-chloromethyl-4-pyrimidinol; 6-(Chloromethyl)-2-(methylsulfanyl)-3,4-dihydropyrimidin-4-one; 6-(Chloromethyl)-2-(methylthio)-4-pyrimidinol
EINECS	Contact for details

Quality Control

Our 6-(Chloromethyl)-2-(Methylthio)Pyrimidin-4(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.