Description

2-Chloromethyl-5-Methyl-4-Oxo-3,4-Dihydro-Thieno[2,3-D]Pyrimidine-6-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 89567-06-6. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular architecture that enables targeted drug development. It is primarily required by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex heterocyclic APIs, particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Research: Serves as a core scaffold for developing new classes of herbicides and fungicides with specific modes of action.
• Chemical Synthesis Building Block: Used in organic synthesis for constructing fused thienopyrimidine ring systems, which are valuable in medicinal chemistry.
• Academic & R&D: Employed in university and corporate research laboratories for studying structure-activity relationships (SAR) and discovering new bioactive molecules.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Chloromethyl-5-Methyl-4-Oxo-3,4-Dihydro-Thieno[2,3-D]Pyrimidine-6-Carboxylic Acid Ethyl Ester
CAS No.	89567-06-6
Molecular Formula	C12H11ClN2O3S
Molecular Weight	298.74 g/mol
Synonyms	Ethyl 2-(Chloromethyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylate; 2-(Chloromethyl)-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-6-carboxylic Acid Ethyl Ester; Thieno[2,3-d]pyrimidine-6-carboxylic Acid Derivative; 89567-06-6; 6-Carbethoxy-2-chloromethyl-5-methyl-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 2-Chloromethyl-5-Methyl-4-Oxo-3,4-Dihydro-Thieno[2,3-D]Pyrimidine-6-Carboxylic Acid Ethyl Ester adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.