Description

6-(Hydroxymethyl)-5-Methylpyrimidine-2,4-Diol is a versatile pyrimidine derivative with significant utility in advanced organic synthesis. This compound serves as a crucial building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its reactive hydroxymethyl and diol functionalities make it an ideal intermediate for researchers and manufacturers requiring high-purity chemical precursors. Key industries that rely on this material include pharmaceutical R&D, fine chemical production, and academic research institutions focused on heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for antiviral or anticancer drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and plant growth regulators due to its pyrimidine core structure.
• Fine Chemical Building Block: Employed in organic synthesis for constructing complex heterocyclic compounds in research and pilot-scale production.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies, leveraging its structural similarity to natural pyrimidine bases.
• Material Science Precursor: Investigated for the development of specialty polymers or ligands for metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for method development and exploratory chemistry in both university and corporate laboratory settings.

Basic Information

Product Name	6-(Hydroxymethyl)-5-Methylpyrimidine-2,4-Diol
CAS No.	89532-98-9
Molecular Formula	C6H8N2O3
Molecular Weight	156.14 g/mol
Synonyms	5-Methyl-6-(hydroxymethyl)uracil; 6-Hydroxymethyl-5-methyluracil; 5-Methyl-6-hydroxymethyluracil; HMU; 2,4-Dihydroxy-5-methyl-6-(hydroxymethyl)pyrimidine; 5-Methyl-6-(hydroxymethyl)-2,4(1H,3H)-pyrimidinedione; NSC 407347
EINECS	Contact for details

Quality Control

Our production of 6-(Hydroxymethyl)-5-Methylpyrimidine-2,4-Diol adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment. We support compliance with cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.