Description

Aspartic Acid, 3-Hydroxy-3-Methyl- is a specialized, non-proteinogenic amino acid derivative with a unique hydroxymethyl side chain. This structural feature makes it a valuable chiral building block and intermediate for the synthesis of more complex bioactive molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for applications in drug discovery and development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified aspartic acid residues, altering peptide stability, solubility, or bioactivity.
• Biochemical Research: Employed as a standard or reagent in enzymatic studies and metabolic pathway research due to its structural similarity to natural amino acids.
• Fine Chemical Synthesis: Acts as a versatile building block for creating complex organic molecules, including natural product analogs and specialty chemicals.
• Ligand for Catalyst Systems: Its chelating properties can be utilized in the development of asymmetric catalysts for stereoselective chemical reactions.

Basic Information

Product Name	Aspartic Acid, 3-Hydroxy-3-Methyl-
CAS No.	89495-39-6
Molecular Formula	C5H9NO5
Molecular Weight	163.13 g/mol
Synonyms	3-Hydroxy-3-methylaspartic acid; (2S,3S)-3-Hydroxy-3-methylaspartic acid; β-Hydroxy-β-methyl-DL-aspartic acid; HMAA; 3-Methyl-3-hydroxyaspartate; 2-Amino-3-hydroxy-3-methylsuccinic acid
EINECS	Contact for details

Quality Control

Our Aspartic Acid, 3-Hydroxy-3-Methyl- is produced under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (specify isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.