Description

Parathyroid Hormone [Asn76]-Human: Fragment 53-84 is a synthetic peptide fragment corresponding to a specific sequence of the human parathyroid hormone (PTH). This compound is of significant value for biochemical and pharmaceutical research, particularly in studies related to calcium metabolism and bone biology. It is primarily needed by research institutions, diagnostic kit manufacturers, and pharmaceutical companies engaged in the development of treatments for metabolic bone disorders such as osteoporosis.

Application

• Biochemical Research: Used as a reference standard and active agent in studies of PTH receptor binding, signal transduction, and calcium homeostasis.
• Diagnostic Development: Serves as a critical antigen or calibrator in the development and validation of immunoassays (e.g., ELISA) for detecting PTH levels in clinical samples.
• Pharmaceutical R&D: Employed in preclinical research for screening and evaluating potential therapeutic compounds targeting the PTH pathway.
• Cell Culture Studies: Applied in in vitro models to investigate the effects of PTH fragments on osteoblast and osteoclast activity.
• Antibody Production: Utilized as an immunogen to generate specific antibodies against the human PTH sequence for research and diagnostic tools.

Basic Information

Product Name	Parathyroid Hormone [Asn76]-Human: Fragment 53-84
CAS No.	89439-30-5
Molecular Formula	C₁₅₀H₂₄₀N₄₆O₄₈S₂
Molecular Weight	3439.9 g/mol
Synonyms	PTH (53-84), human; Parathyroid Hormone Fragment 53-84; hPTH (53-84); [Asn76]hPTH(53-84); Parathyrin (53-84); PTH human fragment 53-84; CAS 89439-30-5
EINECS	Contact for details

Quality Control

Our Parathyroid Hormone [Asn76]-Human: Fragment 53-84 is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including reversed-phase HPLC for purity assessment and mass spectrometry for identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Molecular weight confirmed by mass spectrometry
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.