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1-(4-Bromophenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrido[2,3-D]Pyrimidin-4-One CAS NO 89374-60-7


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CAS No.:89374-60-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-(4-Bromophenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrido[2,3-D]Pyrimidin-4-One is a high-purity, heterocyclic organic compound with a fused pyridopyrimidine core, serving as a critical building block in advanced chemical synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and functional materials. Pharmaceutical R&D teams and fine chemical manufacturers need this precise chemical to drive innovation in drug discovery programs, particularly in oncology and CNS research.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
  • Organic Synthesis Building Block: Used in complex multi-step syntheses to construct fused heterocyclic systems for material science and agrochemical research.
  • Research & Development (R&D): Essential for medicinal chemistry programs in academic, biotech, and pharmaceutical laboratories for structure-activity relationship (SAR) studies.
  • Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
  • Biochemical Tool Compound: Potential use in biochemical assays to study enzyme function and cellular pathways.

Basic Information

Product Name 1-(4-Bromophenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrido[2,3-D]Pyrimidin-4-One
CAS No. 89374-60-7
Molecular Formula C₁₅H₁₀BrN₃OS
Molecular Weight 360.23 g/mol
Synonyms 1-(4-Bromophenyl)-2-thioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-4-one; 4(1H)-Pyrido[2,3-d]pyrimidinone, 1-(4-bromophenyl)-1,2,3,4-tetrahydro-2-thioxo-; 89374-60-7; 1-(p-Bromophenyl)-2-thioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-4-one; 1-(4-Bromophenyl)-2-mercapto-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-4-one; 1-(4-Bromophenyl)-2-sulfanylidene-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidin-4-one
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Quality Control

Our 1-(4-Bromophenyl)-2-Thioxo-1,2,3,4-Tetrahydropyrido[2,3-D]Pyrimidin-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure compliance with exacting standards for research and pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (HPLC) Conforms
Identification (IR) Conforms to reference spectrum
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 1.0%
Total Impurities (HPLC) ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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