Description

1-(4-Methylphenyl)Pyrido[3,2-E]-2-Thiouracil is a specialized heterocyclic organic compound with a fused pyridothiouracil core, serving as a critical building block in advanced pharmaceutical and agrochemical research. Its unique molecular architecture makes it a valuable intermediate for synthesizing novel compounds with potential biological activity. This high-purity chemical is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used as a precursor in the synthesis of novel herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe: Serves as a scaffold for developing molecular probes to study enzyme inhibition or receptor binding mechanisms in biochemical assays.
• Material Science Research: Potential intermediate for creating advanced organic electronic materials or ligands for catalytic systems due to its conjugated system.
• Academic & Institutional R&D: Utilized in university and government laboratories for fundamental research in organic synthesis and medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	1-(4-Methylphenyl)Pyrido[3,2-E]-2-Thiouracil
CAS No.	89374-57-2
Molecular Formula	C15H11N3OS
Molecular Weight	281.33 g/mol
Synonyms	1-(p-Tolyl)pyrido[3,2-e]-2-thiouracil; 1-(4-Methylphenyl)-2-thioxo-1,2-dihydropyrido[3,2-e]pyrimidin-4(3H)-one; 1-(4-Methylphenyl)-1,2-dihydropyrido[3,2-e]-2-thioxopyrimidin-4(3H)-one; Pyrido[3,2-e]-2-thiouracil, 1-(4-methylphenyl)-; 89374-57-2; 1-(4-Methylphenyl)-2-thioxo-1,2-dihydropyrido[3,2-e]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 1-(4-Methylphenyl)Pyrido[3,2-E]-2-Thiouracil is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.