Description

1-(2-Fluorobenzyl)Piperazine is a versatile fluorinated piperazine derivative, a key building block in modern organic synthesis. Its value lies in its ability to introduce a specific fluorobenzyl-piperazine moiety, which is crucial for modulating the biological activity and physicochemical properties of target molecules. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those targeting neurological receptors and kinases.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances metabolic stability and bioavailability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and protein-protein interactions.
• Material Science: Potential monomer or additive in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	1-(2-Fluorobenzyl)Piperazine
CAS No.	89292-78-4
Molecular Formula	C11H15FN2
Molecular Weight	194.25 g/mol
Synonyms	1-[(2-Fluorophenyl)methyl]piperazine; N-(2-Fluorobenzyl)piperazine; 2-Fluorobenzylpiperazine; 1-(2-Fluorobenzyl)piperazine dihydrochloride (salt form); FBP; 2-FBP; (2-Fluorobenzyl)piperazine; Piperazine, 1-[(2-fluorophenyl)methyl]-
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorobenzyl)Piperazine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.