Description

Methyl 2,5,6-Trichloropyrimidine-4-Carboxylate is a high-purity, multi-functional halogenated pyrimidine building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its reactive chlorination pattern enables precise molecular construction. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral, anticancer, and antimicrobial agents, leveraging the pyrimidine core's bioactivity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trichloropyrimidine moiety contributes to efficacy and selectivity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential use in the synthesis of specialized polymers, ligands, or organic electronic materials requiring halogenated heterocycles.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.

Basic Information

Product Name	Methyl 2,5,6-Trichloropyrimidine-4-Carboxylate
CAS No.	89284-85-5
Molecular Formula	C6H3Cl3N2O2
Molecular Weight	241.46 g/mol
Synonyms	Methyl 2,5,6-trichloro-4-pyrimidinecarboxylate; 2,5,6-Trichloropyrimidine-4-carboxylic acid methyl ester; 4-Pyrimidinecarboxylic acid, 2,5,6-trichloro-, methyl ester; Methyl trichloropyrimidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 2,5,6-Trichloropyrimidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.