Description

4-Chloro-6-hydrazino-2-(methylthio)pyrimidine is a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring reactive chloro, hydrazino, and methylthio substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those with pyrimidine-based cores, such as kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Chemical Research & Development: Serves as a fundamental scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential building block for creating specialized polymers or ligands for metal-organic frameworks (MOFs) due to its nitrogen-rich structure.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of heterocyclic dyes and functional colorants.

Basic Information

Product Name	4-Chloro-6-hydrazino-2-(methylthio)pyrimidine
CAS No.	89280-24-0
Molecular Formula	C5H7ClN4S
Molecular Weight	190.65 g/mol
Synonyms	2-(Methylthio)-4-chloro-6-hydrazinopyrimidine; 4-Chloro-2-methylmercapto-6-hydrazinopyrimidine; 4-Chloro-6-hydrazinyl-2-(methylsulfanyl)pyrimidine; 6-Hydrazino-4-chloro-2-methylthiopyrimidine; 2-Methylthio-4-chloro-6-hydrazinopyrimidine; 4-Chloro-6-hydrazino-2-methylthiopyrimidine; 4-Chloro-2-(methylthio)-6-pyrimidinamine, N-amino-
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-hydrazino-2-(methylthio)pyrimidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.